Ursonic Acid

Research use only, not for human use.

Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.

Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.

Cell Proliferation Assay Cell Line:T24 human bladder cancer cells Concentration:12.5-50 μM Incubation Time:48 h Result:Inhibited cell proliferation in a dose-dependent manner.Western Blot Analysis Cell Line:T24 human bladder cancer cells Concentration:12.5-50 μM Incubation Time:48 h Result:Inhibited the anti-apoptotic signaling (pAkt1, pIκBα, NF-κBp65 and Bcl-2).

Animal Model:Adult male albino ratsDosage:5-20 mg/kg Administration:p.o., twice a day, 30 days Result:Increased weight gain and food intake.Decreased AST and ALT activities and total and indirect bilirubin levels.Increased direct bilirubin and levels of non-enzymic antioxidants (GSH, ascorbic acid and a-tocopherol).Decreased lipid peroxidation.

3-Ketoursolic acid

Others

Other Targets

Others

Others-Field

——

6246-46-4

454.69

C30H46O3

>98% (HPLC)

DMSO : 10 mg/mL 21.99 mM;

[C@H]1(CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]3[C@@]4(CCC(=O)C3(C)C)C)C)[C@@H]2[C@H]1C)C)C(=O)O)C

——

(-20℃)

With Ice Pack

≥ 2 years